RegisterLogin

VH032 thiol

CAT: 0804-HY-111823-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111823-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].
CAS Number
[2098836-54-3]
Product Name Alternative
VHL ligand 6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-binding-moiety-3.html
Concentration
10mM
Purity
95.91
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)S)NC(C)=O)=O)=O)C=C2
Molecular Formula
C23H30N4O4S2
Molecular Weight
490.64
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13 (5) :514-521.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under argon)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)

Related Products

CatalogName
HY-120217-01VH032
HY-136164-01VH032-OH
HY-128767-01VH032-PEG3-acetylene
HY-W584534VH032-CH2-Boc
HY-D2413BODIPY FL VH032
HY-W584535VH032-C3-Boc
HY-W584527VH032 analogue-1
HY-168280AS1411-C4-VH032
HY-125905-01VH032-cyclopropane-F
HY-W584528VH032 analogue-2

Alternative Products

CatalogName
T18600VH032 thiol
A19857-10VH032 thiol 10mg
A19857-100VH032 thiol 100mg
A19857-5VH032 thiol 5mg
A19857-1VH032 thiol 1mg
A19857-50VH032 thiol 50mg
MBS3844299-01VH032-thiol-C6-NH2
A19847-10VH032-thiol-C6-NH2 10mg
A19847-1VH032-thiol-C6-NH2 1mg
A19847-5VH032-thiol-C6-NH2 5mg

Popular Products