VH032-OH

• UNSPSC Description:

  VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs[1].

• Target Antigen:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vh032-oh.html

• Smiles:

  O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC(C=CC(C(SC=N2)=C2C)=C3)=C3O)=O)[C@H](C(C)(C)C)NC(C)=O

• Molecular Weight:

  488.60

• References & Citations:

  [1]Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017;8(1):830. Published 2017 Oct 10.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  2244684-42-0