VH032-C3-Boc

• Description:

  VH032-C3-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C3-Boc will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032-C3-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vh032-c3-boc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C) (C) OC (CCCCC (N[C@@H] (C (C) (C) C) C (N1[C@@H] (C[C@H] (C1) O) C (NCC2=CC=C (C3=C (N=CS3) C) C=C2) =O) =O) =O) =O

• Molecular Formula:

  C32H46N4O6S

• Molecular Weight:

  614.80

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2827750-25-2