VH032-C7-COOH

• Description:

  VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/vh032-c7-cooh.html

• Purity:

  99.92

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NCC1=CC=C (C2=C (C) N=CS2) C=C1) [C@H]3N (C ([C@H] (C (C) (C) C) NC (CCCCCCCCC (O) =O) =O) =O) C[C@H] (O) C3

• Molecular Formula:

  C32H46N4O6S

• Molecular Weight:

  614.80

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.2018-06-14.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2172819-77-9