VH032-C7-COOH

• UNSPSC Description:

  VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/vh032-c7-cooh.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCCCCC(O)=O)=O)=O)C[C@H](O)C3

• Molecular Weight:

  614.80

• References & Citations:

  [1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.2018-06-14.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2172819-77-9