PF-4800567

• UNSPSC Description:

  PF-4800567 is a potent and selective inhibitor of casein kinase 1? (CK1?), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).

• Target Antigen:

  Casein Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Stem Cell/Wnt

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/PF-4800567.html

• Purity:

  99.69

• Solubility:

  DMSO : 40 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCL)

• Smiles:

  NC1=C2C(N(C3CCOCC3)N=C2COC4=CC=CC(Cl)=C4)=NC=N1

• Molecular Weight:

  359.81

• References & Citations:

  [1]Walton KM, et al. Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1188296-52-7