MK-7622

• UNSPSC Description:

  MK-7622 (M1 receptor modulator) is a muscarinic M1 receptor positive allosteric modulator[1][2].

• Target Antigen:

  mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/M1-receptor-modulator.html

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C1N([C@@H]2[C@@H](O)CCCC2)C=NC3=C1C=C(CC4=CC=C(C)N=C4)C5=CC=CC=C53

• Molecular Weight:

  399.48

• References & Citations:

  [1]Kuduk Scott D, et al. Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators. From PCT Int. Appl. (2012), WO 2012047702 A1 20120412.|[2]Kuduk Scott D, et al. Benzoquinazolinone derivatives as M1 receptor positive allosteric modulators and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2010), WO 2010059773 A1 20100527.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Phase 2

• CAS Number:

  1227923-29-6