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BI-3812

CAT: 0804-HY-111381-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111381-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-3812, a chemical probe, is a highly efficient BCL6 inhibitor that is capable of suppressing the BTB domain of BCL6, with an IC50 value of ≤ 3 nM, exhibiting antitumor activity[1].
CAS Number
2166387-64-8
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BI-3812.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
ClC1=CN=C(N2CCC(C(N(C)C)=O)CC2)N=C1NC3=CC(C=C(OCC(NC)=O)C(N4C)=O)=C4C(OC)=C3
Molecular Formula
C26H32ClN7O5
Molecular Weight
558.03
Precautions
H315, H319, H320
References & Citations
[1]Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20 (12) :2860-2875.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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