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Sertindole-d4

CAT: 0804-HY-14543S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14543S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sertindole-d4 is the deuterium labeled Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available[1][2].
CAS Number
1794737-42-0
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Autophagy; Dopamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Purity
98.64
Solubility
10 mM in DMSO|DMF : ≥ 15mg/mL|DMSO : ≥ 5mg/mL
Smiles
ClC=1C=C2C(=CN(C2=CC1)C3=CC=C(F)C=C3)C4CCN(C(C(N5C(=O)NCC5)([2H])[2H])([2H])[2H])CC4
Molecular Formula
C24H22D4ClFN4O
Molecular Weight
444.97
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Juruena, M.F., E.P. de Sena, and I.R. de Oliveira, Sertindole in the management of schizophrenia. J Cent Nerv Syst Dis, 2011. 3: p. 75-85.|[3]Kane, J.M. and C.A. Tamminga, Sertindole (Serdolect) : preclinical and clinical findings of a new atypical antipsychotic. Expert Opin Investig Drugs, 1997. 6 (11) : p. 1729-41.|[4]Murdoch, D. and G.M. Keating, Sertindole : a review of its use in schizophrenia. CNS Drugs, 2006. 20 (3) : p. 233-55.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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