Aldosterone-d4

• Description:

  Aldosterone-d4 is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H312, H332

• Target:

  Endogenous Metabolite; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Concentration:

  274.37 μM * 1 mL in Acetonitrile

• Purity:

  99.30

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@@]3([2H])[C@](O)([2H])C([2H])([2H])[C@]4(C=O)[C@@H](C(CO)=O)CC[C@@]4([H])[C@]3([H])CCC1=CC(CC2)=O

• Molecular Formula:

  C21H24D4O5

• Molecular Weight:

  364.47

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nanba K, et al. Aging and Adrenal Aldosterone Production. Hypertension. 2018 Feb;71 (2) :218-223.; Cannavo A, et al. Aldosterone and Mineralocorticoid Receptor System in Cardiovascular Physiology and Pathophysiology. Oxid Med Cell Longev. 2018 Sep 19;2018:12

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported