Aldosterone-d4

• Description :

  Aldosterone-d4 is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H312, H332

• Target :

  Endogenous Metabolite; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Concentration :

  274.37 μM * 1 mL in Acetonitrile

• Purity :

  99.30

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@@]3([2H])[C@](O)([2H])C([2H])([2H])[C@]4(C=O)[C@@H](C(CO)=O)CC[C@@]4([H])[C@]3([H])CCC1=CC(CC2)=O

• Molecular Formula :

  C21H24D4O5

• Molecular Weight :

  364.47

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nanba K, et al. Aging and Adrenal Aldosterone Production. Hypertension. 2018 Feb;71 (2) :218-223.; Cannavo A, et al. Aldosterone and Mineralocorticoid Receptor System in Cardiovascular Physiology and Pathophysiology. Oxid Med Cell Longev. 2018 Sep 19;2018:12

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported