TP-5801

TP-5801

• CAS Number: 2574474-81-8
• UNSPSC Description: TP-5801 is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity[1].
• Target Antigen: STAT
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/tp-5801.html
• Solubility: DMSO : 16.67 mg/mL (ultrasonic)
• Smiles: CN1CCN(C2=C(C)C=C(NC3=NC=C(Br)C(NC4=CC=CN=C4N(C)C)=N3)C(OC)=C2)CC1
• Molecular Weight: 527.46
• References & Citations: [1]Tsz-Yin Chan, et al. TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nat Commun. 2021 Sep 9;12(1):5337.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported