TNFRSF13B

• Description:

  TACI, transmembrane activator and CAML-interactor, is a member of the TNF receptor superfamily (TNFRSF) . Within the TNFRSF, it shares the highest homology with BCMA. TACI and BCMA both bind APRIL and BLyS/BAFF, members of the TNF superfamily. TACI is expressed on the cell surface of B cells and activated, but not resting, T cells. Human and mouse TACI share 54% amino acid sequence identity.

• Synonyms:

  TNFRSF13B; CVID; TACI; CD267; CVID2; TNFRSF14B

• NCBI Gene ID:

  23495

• UniProt:

  O14836

• Accession Number:

  NP_036584.1

• Accession Number mRNA:

  NM_012452.2

• Chromosomal Location:

  17p11.2

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant TNFRSF13B EC domain

• Clone:

  (#9D22)

• Applications:

  WB, IHC (F), N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1