TNFRSF11B

CAT: 0209-103-M480Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M480Size:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Osteoprotegerin (OPG) /osteoclastogenesis inhibitory factor (OCIF) is a member of the TNF receptor superfamily and is now referred to as TNFRSF11B. It is an osteoblast secreted decoy receptor that binds specifically to osteoprotegrin ligand (OPGL/TNFSF11) to inhibit osteoblast maturation. It is also a decoy receptor for TRAIL and inhibits TRAIL-induced apoptosis. Human and mouse OPG share approximately 84% and 94% amino acid sequence identity, respectively, with rat OPG. Natural OPG exists predominantly as disulfide-linked dimers.
Synonyms
Tnfrsf11b; Opg; TR1; OCIF
NCBI Gene ID
18383
UniProt
O08712
Accession Number
NP_032790.3
Accession Number mRNA
NM_008764.3
Chromosomal Location
15 D1; 15
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein TNFRSF11B
Clone
(#13H21)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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