TNFRSF11B

CAT: 0209-101-M655Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M655Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Osteoprotegerin (OPG) /osteoclastogenesis inhibitory factor (OCIF) is a member of the TNF receptor superfamily and is now referred to as TNFRSF11B. It is an osteoblast secreted decoy receptor that binds specifically to osteoprotegrin ligand (OPGL/TNFSF11) to inhibit osteoblast maturation. It is also a decoy receptor for TRAIL and inhibits TRAIL-induced apoptosis. Human and mouse OPG share approximately 84% and 94% amino acid sequence identity, respectively, with rat OPG. Natural OPG exists predominantly as disulfide-linked dimers.
Synonyms
TNFRSF11B; OPG; TR1; OCIF
NCBI Gene ID
4982
UniProt
O00300
Accession Number
NP_002537.3
Accession Number mRNA
NM_002546.3
Chromosomal Location
8q24
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human TNFRSF11B
Clone
(#7D37)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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