TNFSF13B beta

• Description:

  BAFF (B cell activating factor) is a cytokine of the TNF superfamily and essential for the activation, differentiation and survival of B cells, produced predominantly by neutrophils, monocytes, macrophages and dendritic cells in mammals. Synonyms include TNFSF13B (tumor necrosis factor superfamily member 13B), BLyS (B lymphocyte stimulator), TALL-1, zTNF4[2] or CD257 antigen (cluster of differentiation 257) . It is a 285 amino acid long glycoprotein with glycosylation at site 124 and exists as a type 2 transmembrane protein. An isoform exists that lacks the membrane anchor and is therefore freely mobile in the cytosol. It is formed by post-translational modification and contains 152 amino acids.

• Synonyms:

  TNFSF13B (tumor necrosis factor superfamily member 13B), BLyS (B lymphocyte stimulator), TALL-1, zTNF4[2], CD257-Antigen (Cluster of differentiation 257)

• NCBI Gene ID:

  24099

• UniProt:

  Q9WU72

• Accession Number:

  NP_296371.1

• Accession Number mRNA:

  NM_033622.1

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Mouse recombinant protein TNFSF13B

• Clone:

  (#2J39)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2