TNFSF13B (BAFF)

• Description:

  BAFF (B cell activating factor), also known as BlyS (B lymphocyte stimulator) and TALL-1 (TNF- and APOL-related leukocyte expressed ligand 1) is a member of the TNF superfamily designated TNFSF13B. BAFF is expressed by monocytes and dendritic cells in the form of a membrane-anchored homotrimer which may be shed from the cell surface by Furin. BAFF binds BAFF R/TNFRSF13C, BCMA/TNFRSF17 and TACI/TNFRSF13B receptors to regulate B cell homeostasis.

• Synonyms:

  TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20

• NCBI Gene ID:

  10673

• UniProt:

  Q9Y275

• Accession Number:

  NP_006564.1

• Accession Number mRNA:

  NM_006573.4

• Chromosomal Location:

  13q32-q34

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant TNFSF13B (BAFF) (EC domain)

• Clone:

  (#9F42)

• Applications:

  N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2