RegisterLogin

ST2 EC

CAT: 0209-101-M642Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M642Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig) -like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain.ST2L, also known as IL-1 R4, is a transmembrane glycoprotein in the interleukin-1 receptor family. ST2L is expressed on mast cells and Th2 cells as well as on stressed cardiac myocytes and airway epithelia. ST2L associates with IL-1R AcP to form a receptor complex for IL-33. Alternative splicing generates ST2, a secreted isoform that functions as an inhibitor of IL-33 signaling. Within the ECD, mouse ST2L shares 68% aa sequence identity with human ST2L.
Synonyms
IL1RL1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
NCBI Gene ID
9173
UniProt
Q01638
Accession Number
NP_057316.3
Accession Number mRNA
NM_016232.4
Chromosomal Location
2q12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human ST2 extracellular domain
Clone
(#6B72)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
WB: 1:500-1000
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

Related Products

CatalogName
103-M72ST2
101-M835TfR EC
101-M635SLAM EC
101-M629SIGIRR EC
101-M634Siglec-9 EC
101-M632Siglec-5 EC
101-M796IL-6R alpha EC
101-M792IL-5R alpha EC
101-M509IL-7R alpha EC
101-M631Siglec-3 EC (CD33)

Alternative Products

CatalogName
APPDE 300Plasmid DNA Extraction Mini Kit (300prep) (sample size:1~3 ml culture)
APGCK 050GEL/PCR Purification Mini Kit (50prep)
APPCK 200PCR Clean-Up Mini Kit (200prep)
APGPK 200GEL Purification Mini Kit (200prep)
APPGK 100Plant Genomic DNA Extraction Mini Kit (100prep)
APGDC 050FavorPrep Genomic DNA Clean-Up Kit (50prep)
APGDC 200FavorPrep Genomic DNA Clean-Up Kit (200prep)
APVNK 200Viral Nucleic Acid Extraction Kit (200prep), (With Carrier RNA, for low viral load specimen using carrier RNA)
APEBD 002-3Alphagen EtBr Destroyer Sprayer
APRND 001-1Alphagen RNase Destroyer Sprayer

Popular Products