SIGIRR EC

• Description:

  Single Ig domain containing IL-1 receptor-related molecule (SIGIRR) is a subtype of the IL-1 R family that differs from the other members by having only one Ig domain in its extracellular region. SIGIRR is widely expressed and is present in all cells and tissues examined. Mouse and human SIGIRR share 82% amino acid sequence identity. The ligand and signaling mechanism for SIGIRR have not been identified.

• Synonyms:

  SIGIRR; TIR8

• NCBI Gene ID:

  59307

• UniProt:

  Q6IA17

• Accession Number:

  NP_001128526.1

• Accession Number mRNA:

  NM_001135054.1

• Chromosomal Location:

  11p15.5

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human SIGIRR extracellular domain

• Clone:

  (#10D5)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2