NT-3 Recombinant Protein

NT-3 Recombinant Protein

• Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical
• Synonyms: NTF3; NT3; HDNF; NGF2; NGF-2
• CAS Number: 9000-83-3
• NCBI Gene ID: 4908
• UniProt: P20783
• Accession Number: NP_001096124.1
• Accession Number mRNA: NM_001102654
• Gene Location: 12p13
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Chicken, Cow, Dog, Frog, Hamster, Mouse, Pig, Rat, Human, Monkey
• Sequence: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
• Detection Range: Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 120
• Form: Lyophilized
• Molecular Weight: 13.6 kDa
• Shipping Conditions: Room Temperature