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NT-3 Recombinant Protein

CAT: 0209-M10-232Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-232Size:10 µg
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Description
NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
CAS Number
9000-83-3
Synonyms
Ntf3; Nt3; Ntf-3; AI316846; AI835689
NCBI Gene ID
18205
UniProt
P20181
Accession Number
NP_032768.1
Accession Number mRNA
NM_008742.3
Gene Location
6 F3; 6 61.0 cM
Host
E. coli
Origin Species
Mouse
Species Reactivity
Chicken, Cow, Dog, Frog, Hamster, Mouse, Pig, Rat, Human, Monkey
Sequence
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Detection Range
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Endotoxin
< 0.1 ng/µg of protein (<1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Length
120
Form
Lyophilized
Molecular Weight
13.6 kDa
Shipping Conditions
Room Temperature

UniProtKB · P20181

Neurotrophin-3

NTF3_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P20181
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ntf3
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
NT-3
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Technical term

Direct protein sequencingReference proteome

Molecular function

Growth factor

Cellular component

Secreted

Domain

Signal