NT-3 Recombinant Protein

NT-3 Recombinant Protein

• Description: NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
• Synonyms: Ntf3; Nt3; Ntf-3; AI316846; AI835689
• CAS Number: 9000-83-3
• NCBI Gene ID: 18205
• UniProt: P20181
• Accession Number: NP_032768.1
• Accession Number mRNA: NM_008742.3
• Gene Location: 6 F3; 6 61.0 cM
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Chicken, Cow, Dog, Frog, Hamster, Mouse, Pig, Rat, Human, Monkey
• Sequence: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
• Detection Range: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 120
• Form: Lyophilized
• Molecular Weight: 13.6 kDa
• Shipping Conditions: Room Temperature