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NT-3 Recombinant Protein

CAT: 0223-40-565Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-565Size:0.01 mg
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Background
NT-3 is a neurotrophic factor structurally related to β -NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues) .Human and Mouse NT-3 sequences are identical.
CAS Number
9000-83-3
NCBI Gene ID
4908
Swiss Prot
P20783
Accession Number
NP_001096124.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized NT-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted NT-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing NT-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Neurotrophin 3
NCBI Organism
Homo sapiens
Other Product Names
NT3, HDNF, NGF2, NT-3, NGF-2, Neurotrophin-3
Species
Human
Protein ID
156630995
Physical Properties
Lyophilized

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