NT-3 Recombinant Protein

• Background:

  NT-3 is a neurotrophic factor structurally related to β -NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues) .Human and Mouse NT-3 sequences are identical.

• NCBI Gene ID:

  4908

• Swiss Prot:

  P20783

• Accession Number:

  NP_001096124.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized NT-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted NT-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing NT-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Neurotrophin 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NT3, HDNF, NGF2, NT-3, NGF-2, Neurotrophin-3

• Species:

  Human

• Protein ID:

  156630995

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3