NT-4 Recombinant Protein
CAT:
209-100-087S
Size:
2 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NT-4 Recombinant Protein
- Description: NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
- Synonyms: NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
- CAS Number: 9000-83-3
- NCBI Gene ID: 4909
- UniProt: P34130
- Accession Number: NP_006170.1
- Accession Number mRNA: NM_006179.4
- Gene Location: 19q13.3
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Rat, Frog, Human, Mouse
- Sequence: GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
- Detection Range: Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 130
- Form: Lyophilized
- Molecular Weight: 14 kDa
- Shipping Conditions: Room Temperature