Products for Research Use Only
RegisterLogin

Leptin binding protein Recombinant Protein

CAT: 0209-500-046SSize: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-500-046SSize:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recombinant human leptin binding domain (hLBD), is one polypeptide chain containing 208 amino acids and an additional Ala at N-terminus acids. It consists of the cytokine binding domain of leptin receptor (amino acids 428-635 of human leptin receptor and having a molecular mass of ~ 24.5 kDa, It was purified by proprietary chromatographic techniques (see Sandowski et al. J. Biol. Chem. (2002) 277(48):46304-9.
CAS Number
9000-83-3
Synonyms
Lep; ob; obese
NCBI Gene ID
3953
UniProt
P48357
Accession Number
NP_001003679.1
Accession Number mRNA
NM_001003679.3
Host
E. coli
Origin Species
Human
Species Reactivity
Human
Sequence
AIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMD
Detection Range
Recombinant human LBDL is fully biologically active as evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
Endotoxin
< 0.1 ng/µg of protein (<1EU/µg)
Purity
> 98.0% as determined by Gel filtration and SDS-PAGE gel.
Length
208
Form
Lyophilized
Reconstitution
It is recommended to reconstitute the lyophilized hLBD in sterile water adjusted to pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
Molecular Weight
24.5 kDa
Shipping Conditions
Room Temperature
N Terminal Sequence
AIDVNI

UniProtKB · P48357

Leptin receptor

LEPR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48357
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LEPR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LEP-R
EC number
—
Processing
Precursor
Secondary accessions
Q13592, Q13593, Q13594, Q92919, Q92920, Q92921
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Disease

Obesity

Molecular function

Receptor

Related Products

CatalogName
500-071Leptin Recombinant Protein
500-060Leptin Recombinant Protein
500-074SLeptin A Recombinant Protein
500-061Leptin Recombinant Protein
500-058SLeptin Recombinant Protein
500-060SLeptin Recombinant Protein
500-073SLeptin Recombinant Protein
500-058Leptin Recombinant Protein
500-061SLeptin Recombinant Protein
500-071SLeptin Recombinant Protein

Alternative Products

CatalogName
A09M02-NRecombinant folate binding protein
MBS5316645-01Recombinant Heparin Binding Protein
NBP1-84936PEPMRG-binding protein Recombinant Protein Antigen
NBP2-48581PEPS100P binding protein Recombinant Protein Antigen
91-149Retinol-Binding Protein 4 Recombinant Protein
91-749IGF Binding Protein 5 Recombinant Protein
92-063FGF1 Intracellular-Binding Protein Recombinant Protein
91-320IGF Binding Protein 4 Recombinant Protein
91-699IL-22 Binding Protein Recombinant Protein
GTR18910084IL-18 binding protein Recombinant Protein

Popular Products