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I-TAC (CXCL11)

CAT: 0209-M10-086SSize: 5 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-086SSize:5 µg
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Description
I-TAC is a "non-ELR" CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant murine I-TAC is a 9.0 kDa protein containing 79 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
Synonyms
CXCL11
NCBI Gene ID
56066
UniProt
Q9JHH5
Accession Number
NP_062367.1
Accession Number mRNA
NM_019494.1
Chromosomal Location
5; 5 E3
Reactivity
Mouse
Cross Reactivity
Human, Mouse, Monkey, Bacteria
Sequence
FLMFKQGRCLCIGPGMKAVKMAEIEKASVIYPSNGCDKVEVIVTMKAHKRQRCLDPRSKQARLIMQAIEKKNFLRRQNM
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract murine CXCR3 transfected HEK/293 cells using a concentration range of 10.0-100.0 ng/ml.
Length
79
Form
Lyophilized
Molecular Weight
9.0 kDa
Host or Source
E. coli

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