ApoA-I

CAT: 0209-102-P259Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-102-P259Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano) .
Synonyms
APOA1, Apolipoprotein A-I
NCBI Gene ID
335
UniProt
P02647
Accession Number
NP_000030.1
Accession Number mRNA
NM_000039.1
Chromosomal Location
11q23-q24
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human ApoA-I (RT#100-123)
Clone
Rabbit IgG
Applications
WB, ELISA
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
WB: 0,1-0,2 μg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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