I-TAC

• Description:

  I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant human I-TAC is an 8.3 kDa protein containing 73 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

• Synonyms:

  CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B

• NCBI Gene ID:

  6373

• UniProt:

  O14625

• Accession Number:

  NP_005400.1

• Accession Number mRNA:

  NM_005409.4

• Chromosomal Location:

  4q21.2

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human I-TAC

• Clone:

  Rabbit IgG

• Applications:

  ELISA, WB, N

• Purification Method:

  Antigen-affinity purified

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form:

  Lyophilized from PBS

• Buffer:

  PBS

• Reconstitution:

  Water

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source:

  Rabbit