IL-22 BP

CAT: 0209-101-M507Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M507Size:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 22 binding protein (IL-22BP), also known as cytokine receptor family (CRF) 2-10, CRF2-X, and IL-22 RA2, is a secreted glycoprotein belonging to the type II cytokine receptor family. IL-22BP antagonizes IL-22 activity by specifically binding IL-22 with high affinity and blocking its interaction with the cell surface IL-22 receptor heteromeric complex composed of IL-22R and IL-10R2 (IL-10 R beta) . The highest levels of IL-22BP expression are found in breast, lungs and colon.
Synonyms
IL22RA2; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2
NCBI Gene ID
116379
UniProt
Q969J5
Accession Number
NP_443194.1
Accession Number mRNA
NM_052962.2
Chromosomal Location
6q25.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-22BP
Clone
(#6G47)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
Western blotting: 1:500- 1:2000
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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