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IL-1 R1

CAT: 0209-103-M136Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M136Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-1 receptor type I (IL1R-I) is an 80 kD transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. IL1R-I binds the mature forms of IL-1α, IL-1β, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of binding IL-1.
Synonyms
Il1r1; IL-iR; CD121a; CD121b; Il1r-1; Interleukin 1 receptor 1
NCBI Gene ID
16177
UniProt
P13504
Accession Number
NP_032388.1
Accession Number mRNA
NM_008362.2
Chromosomal Location
1 B; 1 19.5 Cm
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Extracellular domain of mouse IL1R-I
Clone
(#11B7)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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