IL-1 alpha

CAT: 0209-103-P10Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-P10Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-1 (IL-1) is a name that designates two proteins, IL-1 alpha and IL-1 beta, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. Although IL-1 production is generally considered to be a consequence of inflammation, recent evidence suggests that IL-1 is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen. Cells in particular known to produce IL-1 include osteoblasts, monocytes, macrophages, keratinocytes, Kupffer cells, hepatocytes, thymic and salivary gland epithelium, Schwann cells, fibroblasts and glia (oligodendroglia, astrocytes and microglia) .
Synonyms
Il1a; Il-1a
NCBI Gene ID
16175
UniProt
P01582
Accession Number
NP_034684.2
Accession Number mRNA
NM_010554
Chromosomal Location
2F;273.0cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse IL-1 alpha
Clone
Rabbit IgG
Applications
ELISA, WB, N
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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