IL-6R alpha

CAT: 0209-103-M544Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M544Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
Synonyms
Il6; Il-6
NCBI Gene ID
16193
UniProt
P08505
Accession Number
NP_112445.1
Accession Number mRNA
NM_031168
Chromosomal Location
5 B1; 5 17.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse IL-6R alpha
Clone
(#27E22)
Applications
ICC, FC
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Related Products

CatalogName
100-160-L500IL-36 alpha (IL-1F6)
100-160-L1000IL-36 alpha (IL-1F6)
100-160-L100IL-36 alpha (IL-1F6)
100-160IL-36 alpha (IL-1F6)
100-160-L250IL-36 alpha (IL-1F6)
100-160SIL-36 alpha (IL-1F6)
100-042-L50IL-1 alpha
100-042-L100IL-1 alpha
100-042-L500IL-1 alpha
103-M426IL-7R alpha

Alternative Products

CatalogName
MBS692632-01IL-6R alpha
208230Interleukin 6 Receptor alpha (Il6ra, D126, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, Il6r, IL-6R, IL-6R, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, MGC30256)
MBS201184-01Recombinant IL-6R alpha
MBS9135826-01Human IL-6R alpha
MBS692633-01IL-6R alpha EC
TD-ATMP00008HURecombinant Human CD126/IL-6R/IL-6R alpha protein
PR15096IL-6/IL-6R alpha, Chimera
E47R23660IL-6R alpha Rabbit pAb
JOT-AP04511-01IL-6R Alpha Polyclonal Antibody
HY-P7223-01IL-6R alpha, Human (CHO)

Popular Products