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IL-1 alpha

CAT: 0209-101-M776Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M776Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
Synonyms
IL1B; IL-1; IL1F2; IL1-BETA
NCBI Gene ID
3553
UniProt
P01583
Accession Number
NP_000566.3
Accession Number mRNA
NM_000575
Chromosomal Location
2q14
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant IL-1alpha
Clone
(#7D35)
Applications
FC, N
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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