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IFN lambda2 (IL-28A) Recombinant Protein

CAT:
209-100-194S
Size:
5 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
IFN lambda2 (IL-28A) Recombinant Protein - image 1

IFN lambda2 (IL-28A) Recombinant Protein

  • Description: IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.
  • Synonyms: IL28A; IFNL2; IL-28A
  • CAS Number: 9000-83-3
  • NCBI Gene ID: 282616
  • UniProt: Q8IZJ0
  • Accession Number: NP_742150.1
  • Accession Number mRNA: NM_172138
  • Gene Location: 19q13.13
  • Host: E. coli
  • Origin Species: Human
  • Species Reactivity: Human
  • Sequence: PVARLHGALP DARGCHIAQF KSLSPQELQA FKRA KDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV
  • Detection Range: Determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. The expected ED50 is 0.3-0.5 ng/ml.
  • Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
  • Purity: > 98% by SDS-PAGE & HPLC analyses
  • Length: 174
  • Form: Lyophilized
  • Molecular Weight: 19.6 kDa
  • Shipping Conditions: Room Temperature