IFN lambda2 (IL-28A) Recombinant Protein
CAT:
209-100-194S
Size:
5 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IFN lambda2 (IL-28A) Recombinant Protein
- Description: IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.
- Synonyms: IL28A; IFNL2; IL-28A
- CAS Number: 9000-83-3
- NCBI Gene ID: 282616
- UniProt: Q8IZJ0
- Accession Number: NP_742150.1
- Accession Number mRNA: NM_172138
- Gene Location: 19q13.13
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: PVARLHGALP DARGCHIAQF KSLSPQELQA FKRA KDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV
- Detection Range: Determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. The expected ED50 is 0.3-0.5 ng/ml.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 174
- Form: Lyophilized
- Molecular Weight: 19.6 kDa
- Shipping Conditions: Room Temperature