Rabbit Anti-Human IFN lambda2 Polyclonal Antibody
CAT:
209-102-P231
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rabbit Anti-Human IFN lambda2 Polyclonal Antibody
- Description: Human/mouse IFN-lambda 2 or IL-28A, IL-28B (or IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
- Synonyms: IL29; IFNL1; IL-29
- CAS Number: 9007-83-4
- NCBI Gene ID: 282616
- UniProt: Q8IZJ0
- Accession Number: NP_742150.1
- Accession Number mRNA: NM_172138
- Gene Location: 19q13.13
- Host: Rabbit
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Recombinant Human IFN-lambda2
- Clone: Rabbit IgG
- Validated Applications: ELISA, WB
- Purification Method: Antigen-affinity purified
- Form: Lyophilized from PBS
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.