IFN gamma

• Description :

  IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.

• Synonyms :

  Ifng; Ifg; IFN-g

• NCBI Gene ID :

  15978

• UniProt :

  P01580

• Accession Number :

  NP_032363

• Accession Number mRNA :

  NM_008337

• Chromosomal Location :

  10 D2; 10 67.0 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Recombinant mouse IFN-gamma

• Clone :

  (#7A13)

• Applications :

  WB, FC

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2