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IFN gamma

CAT: 0209-101-M169Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M169Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.
Synonyms
IFNG; IFG; IFI
NCBI Gene ID
3458
UniProt
P01579
Accession Number
NP_000610.2
Accession Number mRNA
NM_000619
Chromosomal Location
12q14
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IFN-gamma
Applications
ELISA, WB
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Mouse
Isotype
IgG1, kappa

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