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IFN gamma

CAT: 0209-101-M773Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M773Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.
Synonyms
IFNG; IFG; IFI
NCBI Gene ID
3458
UniProt
P01579
Accession Number
NP_000610.2
Accession Number mRNA
NM_000619
Chromosomal Location
12q14
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant IFN gamma
Clone
(#7H58)
Applications
WB, IHC (F), FC, N, Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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