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IFN alpha/beta Receptor 1

CAT: 0209-101-M512Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M512Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs. IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation.
Synonyms
IFNAR1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; Interferon receptor
NCBI Gene ID
3454
UniProt
P17181
Accession Number
NP_000620.2
Accession Number mRNA
NM_000629.2
Chromosomal Location
21q22.1; 21q22.11
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human INF alpha/beta R1 EC domain
Clone
(#8H46)
Applications
WB, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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