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IFN gamma Receptor 1

CAT: 0209-101-M513Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M513Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta) . Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.
Synonyms
IFNGR1; CD119; IFNGR; Interferon gamma receptor 1
NCBI Gene ID
3459
UniProt
P15260
Accession Number
NP_000407.1
Accession Number mRNA
NM_000416.2
Chromosomal Location
6q23.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IFN-gamma R1 EC domain
Clone
(#7K51)
Applications
WB, FC, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1