Kinetin

CAT: 0804-HY-N0160-01Size: 5 gDry Ice: NoHazardous: No
CAT#:0804-HY-N0160-01Size:5 g
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Description
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects[1].
CAS Number
[525-79-1]
Product Name Alternative
6-Furfuryladenine; N6-Furfuryladenine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
SOD
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Kinetin.html
Concentration
10mM
Purity
99.76
Solubility
1M NaOH : 33.33 mg/mL (ultrasonic) |DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
C12=NC=NC(NCC3=CC=CO3)=C1N=CN2
Molecular Formula
C10H9N5O
Molecular Weight
215.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Hsiao G, et al. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol. 2003 Apr 4;465 (3) :281-7.|[2]Axelrod FB, et al. Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomia. Pediatr Res. 2011 Nov;70 (5) :480-3.|[3]Hims MM, et al. Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia. J Mol Med (Berl) . 2007 Feb;85 (2) :149-61.|[4]Griffaut B, et al. Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. Int J Biol Macromol. 2004 Aug;34 (4) :271-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 1

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