Kinetin

• Description :

  Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects[1].

• Product Name Alternative :

  6-Furfuryladenine; N6-Furfuryladenine

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  SOD

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Kinetin.html

• Concentration :

  10mM

• Purity :

  99.76

• Solubility :

  1M NaOH : 33.33 mg/mL (ultrasonic) |DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles :

  C12=NC=NC(NCC3=CC=CO3)=C1N=CN2

• Molecular Formula :

  C10H9N5O

• Molecular Weight :

  215.21

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Hsiao G, et al. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol. 2003 Apr 4;465 (3) :281-7.|[2]Axelrod FB, et al. Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomia. Pediatr Res. 2011 Nov;70 (5) :480-3.|[3]Hims MM, et al. Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia. J Mol Med (Berl) . 2007 Feb;85 (2) :149-61.|[4]Griffaut B, et al. Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. Int J Biol Macromol. 2004 Aug;34 (4) :271-5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 1

• CAS Number :

  [525-79-1]