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GDNFR alpha 4

CAT: 0209-103-M394Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M394Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins.
Synonyms
Gfra4; AW060733; G630015H18Rik
NCBI Gene ID
14588
UniProt
Q9JJT2
Accession Number
NP_064398.1
Accession Number mRNA
NM_020014
Chromosomal Location
2 F1; 2 73.9 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein GFR alpha 4
Clone
(#1M21)
Applications
ELISA, IHC (F)
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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