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IL-4 receptor alpha, soluble

CAT: 0209-102-P106Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-P106Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (γc) . The type I receptor contains, in addition to the γc, an IL-4Rα subunit, whereas the type II receptor contains the IL-13Rα. The secreted extracellular domain of IL-4Rα, called sIL-4Rα, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naïve CD4+ T cells and class switching to IgG1 and IgE.
Synonyms
Soluble Interleukin-4Rα, soluble IL-4 Receptor alpha, CD124
NCBI Gene ID
3566
UniProt
P24394
Accession Number
NP_000409.1
Accession Number mRNA
NM_000418
Chromosomal Location
16p12.1-p11.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
CHO cells derived Recombinant Human IL-4 Receptor α
Clone
Rabbit IgG
Applications
WB, ELISA
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized
Reconstitution
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit
Isotype
Rabbit IgG

Alternative Products

CatalogName
360551-01IL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-, R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha) discontinued
MBS692482-01Human IL-4 receptor alpha (CD124), soluble
MBS6382817-01IL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/pr
128472-APCIL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP) (APC)
128472-HRPIL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP) (HRP)
128472-PEIL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP) (PE)
128472IL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP)
128471-FITCIL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP) (FITC)