FGF-20 Recombinant Protein

FGF-20 Recombinant Protein

• Description: FGF-20 is secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c and is expressed during limb and brain development. Recombinant human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.
• Synonyms: FGF20; FGF-20
• CAS Number: 9000-83-3
• NCBI Gene ID: 26281
• UniProt: Q9NP95
• Accession Number: NP_062825.1
• Accession Number mRNA: NM_019851
• Gene Location: 8p22
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Monkey, Mouse
• Sequence: PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT
• Detection Range: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 90% by SDS-PAGE & HPLC analyses
• Length: 209
• Form: Lyophilized
• Buffer: 25mM Tris, pH 7.6 + 1.5M NaCl
• Reconstitution: Reconstitute in 10mM Tris, pH 7.6, to a concentration of 0.1-1.0 mg/ml
• Molecular Weight: 23.2 kDa
• Shipping Conditions: Room Temperature