FGF-8a Recombinant Protein

FGF-8a Recombinant Protein

• Description: FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. CHO cell-derived recombinant human FGF-8a is a 21.2 kDa protein consisting of 182 amino acid residues.
• Synonyms: Fibroblast Growth Factor-8, FGF-8a, AIGF, HBGF-8
• CAS Number: 9000-83-3
• NCBI Gene ID: 2253
• UniProt: P55075-2
• Accession Number: NP_149355.1
• Accession Number mRNA: NM_033165.3
• Host: CHO
• Origin Species: Human
• Species Reactivity: Human
• Sequence: QHVREQSLVT DQLSRRLIRT YQLYSRTSGK HVQVLANKRI NAMAEDGDPF AKLIVETDTF GSRVRVRGAE TGLYICMNKK GKLIAKSNGK GKDCVFTEIV LENNYTALQN AKYEGWYMAF TRKGRPRKGS KTRQHQREVH FMKRLPRGHH TTEQSLRFEF LNYPPFTRSL RGSQRTWAPE PR
• Detection Range: Determined by a cell proliferation assay using balb/c 3T3 cells.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 95% by SDS-PAGE & HPLC analyses
• Length: 182
• Form: Lyophilized
• Molecular Weight: 21.2 kDa
• Shipping Conditions: Room Temperature