FGF-5 Recombinant Protein

FGF-5 Recombinant Protein

• Description: FGF-5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.
• Synonyms: FGF5; HBGF-5; Smag-82
• CAS Number: 9000-83-3
• NCBI Gene ID: 2250
• UniProt: P12034
• Accession Number: NP_004455
• Accession Number mRNA: NM_004464
• Gene Location: 4q21
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG
• Detection Range: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 95% by SDS-PAGE & HPLC analyses
• Length: 252
• Form: Lyophilized
• Buffer: 5 mM Tris, pH 7.2 + 50 mM NaCl
• Molecular Weight: 27.6 kDa
• Shipping Conditions: Room Temperature