CD86

CAT: 0209-101-M317Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M317Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
B7-1 and B7-2 (CD86), together with their receptors CD28 and CTLA4, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. Although both CTLA4 and CD28 can bind to the same ligands, CTLA4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B72 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be upregulated through interferon gamma. B7-1 and B7-2 are both members of the immunoglobulin superfamily.
Synonyms
B7-2; B70; Ly-58
NCBI Gene ID
942
UniProt
P42081
Accession Number
NP_795711.1
Accession Number mRNA
NM_175862.4
Chromosomal Location
3q21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CD86 EC domian
Clone
(#7F35)
Applications
https://www.reliatech.de/pub/media/ds/ma/101-M317.pdf
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

Related Products

CatalogName
101-M316CD83
103-M106CD8a
101-M698UPAR (CD87)
101-M315CD80 (B7-1)
103-M144CD80 (B7-1)
101-M314CD8 alpha
600-060-L100CD80 / B7-1 Protein
M60-054-L1000CD80 / B7-1 Protein (hFc Tag)
600-059-L100CD80 / B7-1 Protein (His Tag)
M60-054-L100CD80 / B7-1 Protein (hFc Tag)

Alternative Products

CatalogName
abx456301-01CD86 Antigen (CD86) Antibody
MBS438023-01CD86
477551CD86 (T-Lymphocyte Activation Antigen CD86, CD86 Molecule)
YP-W28383-01Mouse CD86 (CD86) ELISA Kit
PT_74630-01CD86, Rat Anti-Mouse (CD86 Antibody)
201-04-1035Bovine CD86 molecule (CD86) ELISA Kit
abx257247Cow CD86 Molecule (CD86) ELISA Kit
MBS9403984-01CD86 Antibody

Popular Products