CD50

CAT: 0209-101-M309Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0209-101-M309Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Intercellular adhesion molecule 3 (ICAM-3), also known as CD50, is a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and alphad/beta2. ICAM-3 is expressed on leukocytes and epidermal Langerhans cells.

Synonyms

ICAM3; CD50; CDW50; ICAM-R

NCBI Gene ID

3385

UniProt

P32942

Accession Number

NP_002153.2

Accession Number mRNA

NM_002162.3

Chromosomal Location

19p13.3-p13.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant CD50 EC domain

Clone

(#8V23)

Applications

WB, N

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

UniProtKB · P32942

Intercellular adhesion molecule 3

ICAM3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P32942
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ICAM3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: ICAM-3
EC number: —
Processing: Precursor
Secondary accessions: Q6PD68

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell adhesionPhagocytosis

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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101-M814	NCAM-1 (CD56)
103-M97	ICAM-1 (CD54)
101-M521	Integrin alpha V (CD51)
600-142-L100	ICAM-1 / CD54 Protein (ECD)
600-141-L50	ICAM-1 / CD54 Protein (His Tag)
600-139-L1000	ICAM-1 / CD54 Protein (hFc Tag)

Alternative Products

Catalog	Name
309912-01	CD50
GTR17856974	CD50 Antibody
534408-01	CD50 discontinued
MBS4380596-01	CD50/ICAM3