ICAM-1 (CD54)

• Description :

  Intercellular adhesion molecule 1 (ICAM-1), also known as CD54, binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface.

• Synonyms :

  Icam1; CD54; Ly-47; Icam-1; MALA-2

• NCBI Gene ID :

  15894

• UniProt :

  P13597

• Accession Number :

  NP_034623.1

• Accession Number mRNA :

  NM_010493.2

• Chromosomal Location :

  9 A3; 9 7.0 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Cytokine stimulated Mouse Endothelial cells

• Clone :

  (#MAB0802)

• Applications :

  IHC (P), FC

• Purification Method :

  Protein G/A chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS (sterile)

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2