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CCL-7 (MCP-3)

CAT: 0209-101-M275Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M275Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2. CCL7 cDNA encodes a 99 amino acid residue precursor protein from which the N-terminal 23 amino acid residues are cleaved to generate the 76 amino acid residue mature CCL7. Mature CCL7 contains a potential N-linked and several possible O-linked glycosylation sites. Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
Synonyms
CCL7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7
NCBI Gene ID
6354
UniProt
P80098
Accession Number
NP_006264
Accession Number mRNA
NM_006273
Chromosomal Location
17q11.2-q12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CCL-7
Clone
(#6J48)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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