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CP-346086

CAT: 0804-HY-113955-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113955-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1].
CAS Number
186390-48-7
Product Name Alternative
MSC2363318A
UNSPSC
12352005
Target
Microsomal Triglyceride Transfer Protein (MTP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cp-346086.html
Purity
99.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)NC3=CC4=C(CN(CC5=NC=NN5)CC4)C=C3
Molecular Formula
C26H22F3N5O
Molecular Weight
477.48
References & Citations
[1]Chandler CE, et, al. CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans. J Lipid Res. 2003 Oct;44 (10) :1887-901.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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