MK-6240

• UNSPSC Description :

  MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs[1].

• Target Antigen :

  Tau Protein

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/MK-6240.html

• Purity :

  99.60

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles :

  NC1=C(C=CC2=C1C=C(N=C2)N3C=CC4=C3C=NC=C4)F

• Molecular Weight :

  278.28

• References & Citations :

  [1]Walji AM, et al. Discovery of 6-(Fluoro-(18)F)-3- (1H-pyrrolo [2,3-c]pyridin-1-yl) isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 May 26;59(10):4778-89.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information :

  Phase 3

• CAS Number :

  [1841078-87-2]